A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in […] After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson’s disease (PD) are now actively being explored. In this special supplement to the […] Patients with abnormal variants (mutations) in the DPYD gene are known to be at risk for severe toxicity from treatment with 5-fluorouracil or capecitabine—chemotherapies commonly […] A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a […] Roughly 1 out of 15,000 people born suffer from Facioscapulohumeral Muscular Dystrophy (FSHD), a rare disease that starts with the progressive weakening of facial muscles […] St. Jude Children's Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression for treatment of disorders such […] Our bodies and behaviors often seem to have rhythms of their own. Why do we go to the bathroom at the same time every day? […] Severe coronavirus disease 2019 (COVID-19) is associated with the development of acute respiratory distress syndrome (ARDS), characterized by exacerbated inflammation in the lungs and significantly […] A pioneering study, published in Scientific Reports, found that the Parkinon’s gene PINK1 is important for the generation of dopamine-producing neurons throughout life, and is […] A research team at the Greenwood Genetic Center (GGC) has identified the mechanism that causes movement disorders in patients with mutations in the NUS1 gene. […]
Researchers discover how a genetic mutation in mice and monkeys interferes with viruses
Pipeline of cell and gene therapies holds promise for repairing the Parkinson’s-damaged brains
Rare gene mutations lead to greatly increased risk of fatal chemotherapy toxicity
Known regulatory gene appears to be a master gear in the circadian clock
Researchers use gene editing to tackle facioscapulohumeral muscular dystrophy
High-throughput system can regulate gene expression for treating sickle cell disease, beta thalassemia
Researchers investigate how the brain's circadian rhythm control center regulates behavior
SARS-CoV-2 inhibits the cellular response to interferon
Parkinson’s gene may impair how new neurons are made throughout our lifetime
Study uncovers mechanism that causes genetic movement disorder
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